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Press Release

OraSure Technologies Quarterly Conference Call Invitation; 2005 Third Quarter Earnings Conference Call Wednesday November 9, 2005, 5:00 p.m. ET

October 24, 2005 at 6:01 AM EDT

BETHLEHEM, Pa.--(BUSINESS WIRE)--Oct. 24, 2005--OraSure Technologies, Inc. (NASDAQ:OSUR) has scheduled its regular quarterly earnings conference call covering 2005 third quarter financial results for 5:00 pm ET (2:00 pm PT) on Wednesday, November 9, 2005.

November 9, 2005 Schedule
-------------------------

4:00 p.m. ET 2005 third quarter financial results will be
distributed by Business Wire

4:50 p.m. ET To participate in the conference call, dial
888-742-2024 (Domestic) or 706-643-0033 (International)
and reference OraSure Technologies

5:00 p.m. ET Conference call and simultaneous Webcast begins

The conference call will also be webcast live and may be accessed on the Investor Relations page of OraSure's website, www.orasure.com. Please click on the webcast link and follow the prompts for registration and access 10 minutes prior to the call.

If you are unable to participate, a replay of the call will be archived on OraSure's website shortly after the call has ended and will be available for seven days. A replay of the call can also be accessed until midnight, November 14, 2005, by dialing 800-642-1687 (Domestic) or 706-645-9291 (International) and entering the Conference ID #1701906.

CONTACT: OraSure Technologies, Inc.
Ronald H. Spair, 610-882-1820
investorinfo@orasure.com

SOURCE: OraSure Technologies, Inc.

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