OraSure Technologies Quarterly Conference Call Invitation; 2004 Fourth Quarter and Year End Earnings Conference Call Thursday, February 10, 2005, 5:00 p.m. ET

BETHLEHEM, Pa., Jan 27, 2005 /PRNewswire-FirstCall via COMTEX/ -- OraSure Technologies, Inc. (Nasdaq: OSUR) has scheduled its regular quarterly earnings conference call covering 2004 fourth quarter and full-year financial results for 5:00 pm ET (2:00 pm PT) on Thursday, February 10, 2005.

February 10, 2005 Schedule

     4:00 p.m. ET   2004 fourth quarter and full-year financial results will
                    be distributed by Business Wire

     4:50 p.m. ET   To participate in the conference call, dial 888-742-2024
                    (Domestic) or 706-643-0033 (International) and reference
                    OraSure Technologies

     5:00 p.m. ET   Conference call and simultaneous Webcast begins

The conference call will also be webcast live and may be accessed on the Investor Relations page of OraSure's website, http://www.orasure.com. Please click on the webcast link and follow the prompts for registration and access 10 minutes prior to the call.

If you are unable to participate, a replay of the call will be archived on OraSure's website shortly after the call has ended and will be available for seven days. A replay of the call can also be accessed until midnight, February 13, 2005, by dialing 800-642-1687 (Domestic) or 706-645-9291 (International) and entering the Conference ID #3409876.

COMPANY CONTACT: Ronald H. Spair, Chief Financial Officer, OraSure Technologies, Inc. 610-882-1820, investorinfo@orasure.com

SOURCE OraSure Technologies, Inc.

Ronald H. Spair, Chief Financial Officer, OraSure Technologies, Inc.,
+1-610-882-1820, investorinfo@orasure.com