OraSure Technologies Quarterly Conference Call Invitation; 2004 Third Quarter Earnings Conference Call Tuesday, November 2, 2004, 5:00 p.m. ET

BETHLEHEM, Pa.--(BUSINESS WIRE)--Oct. 22, 2004--OraSure Technologies, Inc. (NASDAQ NM:OSUR) has scheduled its regular quarterly earnings conference call covering third quarter 2004 financial results for 5:00 pm ET (2:00 pm PT) on Tuesday, November 2, 2004.

                       November 2, 2004 Schedule
                       -------------------------

4:00 p.m. ET    Q3 2004 results will be distributed by Business Wire

4:50 p.m. ET    To participate in the conference call, dial
                888-742-2024 (Domestic) or 706-643-0033
                (International) and reference OraSure Technologies

5:00 p.m. ET    Conference call and simultaneous Webcast begins

The conference call will also be webcast live and may be accessed on the Investor Relations page of OraSure's website, www.orasure.com. Please click on the webcast link and follow the prompts for registration and access 10 minutes prior to the call.

If you are unable to participate, a replay of the call will be archived on OraSure's website shortly after the call has ended and will be available for seven days. A replay of the call can also be accessed until November 5, 2004, by dialing 800-642-1687 (Domestic) or 706-645-9291 (International) and enter the Conference ID #211244.

    CONTACT: OraSure Technologies, Inc.
             Ronald H. Spair, 610-882-1820
             investorinfo@orasure.com

    SOURCE: OraSure Technologies, Inc.