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Press Release

OraSure Technologies Earnings Conference Call Invitation

July 18, 2008 at 2:30 PM EDT

2008 Second Quarter Earnings Conference Call
Tuesday, August 5, 2008, 5:00 p.m. ET

BETHLEHEM, Pa.--(BUSINESS WIRE)--July 18, 2008--OraSure Technologies, Inc. (NASDAQ:OSUR) has scheduled its regular quarterly earnings conference call covering 2008 second quarter financial results for 5:00 pm ET (2:00 pm PT) on Tuesday, August 5, 2008. An update on certain business developments will also be provided.

                       August 5, 2008 Schedule
                       -----------------------

       4:00 p.m. ET   2008 second quarter financial results will be
                       distributed by Business Wire

       4:50 p.m. ET   To participate in the conference call, dial 888-
                       742-2024 (Domestic) or 706-643-0033
                       (International) and reference Conference ID
                       #56781070.

       5:00 p.m. ET   Conference call and simultaneous Webcast begins

The conference call will also be webcast live and may be accessed on the Investor Relations page of OraSure's website, www.orasure.com. Please click on the webcast link and follow the prompts for registration and access 10 minutes prior to the call.

If you are unable to participate, a replay of the call will be archived on OraSure's website shortly after the call has ended and will be available for seven days. A replay of the call can also be accessed until midnight, August 12, 2008, by dialing 800-642-1687 (Domestic) or 706-645-9291 (International) and entering the Conference ID # 56781070.

CONTACT: OraSure Technologies, Inc.
Judy Clarke, 610-882-1820
investorinfo@orasure.com

SOURCE: OraSure Technologies, Inc.

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