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Press Release

OraSure Technologies Earnings Conference Call Invitation

April 23, 2008 at 10:00 AM EDT

2008 First Quarter Earnings Conference Call

Tuesday, May 6, 2008, 5:00 p.m. ET

BETHLEHEM, Pa.--(BUSINESS WIRE)--April 23, 2008--OraSure Technologies, Inc. (NASDAQ:OSUR) has scheduled its regular quarterly earnings conference call covering 2008 first quarter financial results for 5:00 pm ET (2:00 pm PT) on Tuesday, May 6, 2008. An update on certain business developments will also be provided.

                         May 6, 2008 Schedule
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4:00 p.m. ET 2008 first quarter financial results will be distributed
              by Business Wire

4:50 p.m. ET To participate in the conference call, dial 888-742-2024
              (Domestic) or 706-643-0033 (International) and reference
              Conference ID #43942293.

5:00 p.m. ET Conference call and simultaneous Webcast begins

The conference call will also be webcast live and may be accessed on the Investor Relations page of OraSure's website, www.orasure.com. Please click on the webcast link and follow the prompts for registration and access 10 minutes prior to the call.

If you are unable to participate, a replay of the call will be archived on OraSure's website shortly after the call has ended and will be available for seven days. A replay of the call can also be accessed until midnight, May 13, 2008, by dialing 800-642-1687 (Domestic) or 706-645-9291 (International) and entering the Conference ID # 43942293.

CONTACT: OraSure Technologies, Inc.
Judy Clarke, 610-882-1820
investorinfo@orasure.com

SOURCE: OraSure Technologies, Inc.

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