|Clovis Oncology and Strata Oncology Announce Collaboration to Accelerate Enrollment in Rucaparib Prostate Cancer Development Program|
Strata Trial to Identify Genetically Selected Patients Eligible for Enrollment in Clovis’ TRITON Studies in Advanced Prostate Cancer
Rucaparib is an oral inhibitor of poly ADP-ribose polymerase (PARP),
approved in the U.S. in 2016 as Rubraca™ (rucaparib) as
monotherapy for the treatment of patients with deleterious BRCA mutation
(germline and/or somatic) associated advanced ovarian cancer, who have
been treated with two or more chemotherapies, and selected for therapy
Strata Oncology is conducting the Strata Trial, an observational study that provides next-generation sequencing at no cost to all advanced cancer patients at its affiliated cancer centers and hospitals. Strata then refers patients with selected mutations to physicians involved in its pharmaceutical partners’ targeted clinical trials. Strata seeks to fulfill the promise of precision medicine by improving the number of patients identified with specific mutations appropriate for ongoing clinical trials.
Under the terms of the agreement, Strata will exclusively refer BRCA and ATM-mutated advanced prostate cancer patients for consideration of enrollment to Clovis’ TRITON2 and TRITON3 clinical trials of rucaparib. The Strata Trial is available at an expanding network of select cancer centers and hospitals nationwide.
“We’re delighted to work with
“Following rucaparib’s initial U.S. approval in ovarian cancer, we are
committed to rapidly enrolling additional trials and expanding rucaparib
development into broader indications, including prostate,” said
About Strata Oncology
Strata Oncology is a precision medicine company dedicated to transforming cancer care by expanding patient access to precision medicine clinical trials. The Strata Trial provides no-cost tumor sequencing to patients with advanced cancer, while offering pharmaceutical companies exclusive access to stratified patient populations to shorten clinical development timelines. Strata aims to accelerate the approval of new medicines for cancer patients by bringing together a collaborative network of key stakeholders including patients, providers and pharmaceutical companies. For more information visit www.strataoncology.com.
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