Market Leader in Asbestos Claims Administration to Highlight the Value of Accurate Mesothelioma Diagnostics With Defendants and Insurers
PHILADELPHIA, PA and REHOVOT, ISRAEL, Jun 14, 2011 (MARKETWIRE via COMTEX) --
Rosetta Genomics (NASDAQ: ROSG), a leading developer and provider
of microRNA-based molecular diagnostic tests, announces the signing
of an exclusive marketing agreement with PACE Claims Services LLC
(PACE) to provide educational and marketing services on behalf of
Rosetta Genomics' miRview(R) meso diagnostic test to defendants and
insurers in mesothelioma legal cases worldwide. PACE is a
wholly-owned subsidiary of Navigant Consulting, Inc. (NYSE: NCI) and
is the market leader in asbestos claims administration.
In a study published in The Journal of Molecular Diagnostics in
September 2010, miRview(R) meso was shown to be a highly sensitive
test for differentiating mesothelioma from carcinomas in the lung or
pleura, with a sensitivity of 100% and a specificity of 94%.
Through the partnership, PACE will market miRview meso as a key tool
in better diagnosing varying forms of cancer, thereby potentially
saving defendants who might otherwise pay millions to claimants who
were misdiagnosed with mesothelioma. Among the ways PACE will share
details of the product are targeted client outreach via email, phone,
conferences and in-person meetings; as well as leveraging other
strategies that target mesothelioma litigation defendants.
The single largest risk factor for developing mesothelioma is
exposure to asbestos, which has a characteristic latency period of 20
to 50 years between exposure and the onset of the malignancy. The
widespread use of asbestos from the 1940s through the 1970s is now
resulting in a growing number of worldwide cases of mesothelioma.
According to the World Health Organization database, between 2000 and
2004 there were approximately 2,500 mesothelioma deaths per year in
the U.S. There were approximately 27,000 mesothelioma deaths per year
outside the U.S. during that same period.
"With mesothelioma on the rise outside the U.S., and new cases of
this cancer coming to light on a regular basis, mesothelioma
litigation has become a multi-billion dollar industry in compensation
claims against manufacturers of asbestos as well as the companies
that allegedly exposed staff to this substance without adequate
protection and warning. As a result, it is increasingly important to
determine with certainty whether a carcinoma is mesothelioma or a
different carcinoma of the lung or pleura. We look forward to
marketing miRview(R) meso to the various defendants and insurers,
many of whom are existing clients of PACE. We believe defendants and
insurers will welcome a diagnostic that can objectively provide an
appropriate medical diagnosis with a high level of accuracy,
potentially saving these companies millions of dollars in legal
settlements for claims that otherwise could have been misdiagnosed as
mesothelioma," commented Bradley Drew, Managing Director of PACE
Claims Services, LLC.
"As the market leader in asbestos claims administration, PACE is the
ideal partner to bring miRview(R) meso to the defendants and insurers
who risk paying costly judgments and settlements for lung cancer
cases that may not be mesothelioma. Rosetta Genomics' microRNAs, with
their high tissue sensitivity and specificity, are ideal tools for
objectively and accurately ruling out mesothelioma. The potential
revenue opportunity for miRview(R) meso in this niche market is
significant with more than 2,000 new claims filed in the U.S. each
year and more than 8,000 mesothelioma claims in the U.S. currently
pending. Ruling out mesothelioma may save defendants and insurers
significant amounts of money," noted Kenneth A. Berlin, President and
Chief Executive Officer of Rosetta Genomics.
"This marketing agreement expands our commercial strategy for the
miRview(R) product line and augments our recently launched sales
efforts in the U.S. aimed at marketing our diagnostic products to
pathologists and oncologists at leading cancer institutions and
clinics," added Mr. Berlin.
About miRview(R) Products
miRview(R) are a series of microRNA-based
diagnostic products offered by Rosetta Genomics. miRview(R) mets and
miRview(R) mets^2 accurately identify the primary tumor site in
metastatic cancer and CUP. miRview(R) squamous accurately identifies
the squamous subtype of non-small cell lung cancer, which carries an
increased risk of severe or fatal internal bleeding and poor response
to treatment for certain therapies. miRview(R) meso diagnoses
mesothelioma, a cancer connected to asbestos exposure. miRview(R)
tests are designed to provide objective diagnostic data; it is the
treating physician's responsibility to diagnose and administer the
appropriate treatment. In the U.S. alone, Rosetta Genomics estimates
that approximately 200,000 patients a year may benefit from the
miRview(R) mets and miRview(R) mets^2 test, 60,000 from miRview(R)
squamous and 60,000 from miRview(R) meso (for clinical use). The
Company's tests are offered directly by Rosetta Genomics in the U.S.,
and through distributors around the globe. For more information,
please visit www.mirviewdx.com. Parties interested in ordering the
test can contact Rosetta Genomics at (215) 382-9000 ext. 309.
About microRNAs
microRNAs (miRNAs) are recently discovered, small
RNAs that act as master regulators of protein synthesis, and have
been shown to be highly effective biomarkers. The unique advantage of
microRNAs as biomarkers lies in their high tissue specificity, and
their exceptional stability in the most routine preservation methods
for biopsies, including Formalin Fixed Paraffin Embedded (FFPE) block
tissue and fine needle aspirate (FNA) cell blocks. It has been
suggested that their small size (19 to 21 nucleotides) enables them
to remain intact in FFPE blocks, as opposed to messenger RNA (mRNA),
which tends to degrade rapidly. In addition, early preclinical data
has shown that by controlling the levels of specific microRNAs,
cancer cell growth may be reduced. To learn more about microRNAs,
please visit www.rosettagenomics.com.
About Rosetta Genomics
Rosetta Genomics develops and commercializes
a full range of microRNA-based molecular diagnostics. Founded in
2000, the company's integrative research platform combining
bioinformatics and state-of-the-art laboratory processes has led to
the discovery of hundreds of biologically validated novel human
microRNAs. Building on its strong patent position and proprietary
platform technologies, Rosetta Genomics is working on the application
of these technologies in the development and commercialization of a
full range of microRNA-based diagnostic tools. The Company's miRview
product line is commercially available through its Philadelphia-based
CAP-accredited, CLIA-certified lab. To learn more, please visit
www.rosettagenomics.com.
About PACE Claims Services
PACE Claims Services, a subsidiary of
Navigant Consulting, Inc. (NYSE: NCI), is a recognized leader in mass
tort claims administration. Formed in the early 1980s to support
clients facing asbestos data management and claims administration
challenges, PACE professionals combine proven experience with modern
systems and technology to provide clients with a cost effective
solution to address their mass tort litigation needs without
sacrificing quality. Clients include defendant companies, insurers,
financial institutions and other entities.
Forward-Looking Statements
Various statements in this release
concerning Rosetta's future expectations, plans and prospects,
including without limitation, statements relating to the potential
revenue opportunity for miRview(R) meso in the asbestos claims market
and the potential of microRNAs in the diagnosis and treatment of
disease, constitute forward-looking statements for the purposes of
the safe harbor provisions under The Private Securities Litigation
Reform Act of 1995. Actual results may differ materially from those
indicated by these forward-looking statements as a result of various
important factors, including risks related to: Rosetta's approach to
discover microRNA technology and to work on the application of this
technology in the development of novel diagnostics and therapeutic
tools, which may never lead to commercially accepted products or
services; Rosetta's ability to obtain, maintain and protect its
intellectual property; Rosetta's ability to enforce its patents
against infringers and to defend its patent portfolio against
challenges from third parties; Rosetta's need and ability to obtain
additional funding to support its business activities; Rosetta's
dependence on third parties for development, manufacture, marketing,
sales, and distribution of products; Rosetta's ability to
successfully develop its products and services; Rosetta's ability to
obtain regulatory clearances or approvals that may be required for
its products and services; the ability to obtain coverage and
adequate payment from health insurers for the products and services
comprising Rosetta's technology; competition from others using
technology similar to Rosetta's and others developing products for
similar uses; Rosetta's dependence on collaborators; and Rosetta's
short operating history; as well as those risks more fully discussed
in the "Risk Factors" section of Rosetta's Annual Report on Form 20-F
for the year ended December 31, 2010 as filed with the Securities and
Exchange Commission. In addition, any forward-looking statements
represent Rosetta's views only as of the date of this release and
should not be relied upon as representing its views as of any
subsequent date. Rosetta does not assume any obligation to update any
forward-looking statements unless required by law.
Company Contact:
Rosetta Genomics
Ken Berlin
President & CEO
(215) 382-9000 ext. 326
investors@rosettagenomics.com
Investor Contacts:
Lippert/Heilshorn & Associates
Anne Marie Fields
(212) 838-3777
afields@lhai.com
Bruce Voss
(310) 691-7100
bvoss@lhai.com
SOURCE: Rosetta Genomics, Ltd.
mailto:investors@rosettagenomics.com
mailto:afields@lhai.com
mailto:bvoss@lhai.com