|  | | Q. | Where is Targacept incorporated? | | A. | We are incorporated in Delaware. |
| Q. | Where is Targacept located? | | A. | Our headquarters are located at 200 East First Street, Suite 300, Winston-Salem, North Carolina 27101. |
| Q. | When did Targacept go public and at what price? | | A. | Our common stock began trading on April 12, 2006. The initial public offering price was $9.00 per share. |
| Q. | Who were the managing underwriters for the IPO? | | A. | The managing underwriters for our IPO were Deutsche Bank Securities Inc., book-running manager, Pacific Growth Equities, LLC, co-lead, CIBC World Markets Corp. and Lazard Capital Markets LLC. |
| Q. | Where is Targacept’s stock listed? | | A. | Our common stock is listed on the Nasdaq Global Market under the symbol TRGT. |
| Q. | I would like to buy shares of Targacept’s common stock. Can I purchase shares directly from the company? | | A. | No. Currently, we do not have a direct purchase program available. |
| Q. | Who is Targacept's transfer agent? | | A. | American Stock Transfer and Trust Company
Transfer Agent and Registrar
59 Maiden Lane
New York, NY 10038
1-800-937-5449
www.amstock.com
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| Q. | What is the CUSIP number for Targacept’s common stock? | | A. | The CUSIP number for our common stock is 87611R 30 6. |
| Q. | I've lost my stock certificates. How can I replace them? | | A. | To replace lost stock certificates, contact American Stock Transfer and Trust Company (contact information provided above). There may be a fee involved for replacing lost stock certificates. |
| Q. | When do Targacept’s fiscal year and fiscal quarters end? | | A. | Our fiscal year ends on December 31 of each year. Our fiscal quarters end on March 31, June 30, September 30 and December 31 of each year. |
| Q. | Who is Targacept’s independent auditor? | | A. | Ernst & Young LLP
202 CentrePort Drive
Suite 200
Greensboro, North Carolina 27409
336-662-6600
www.ey.com
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