| DATE | TITLE | |
| December 21, 2004 | POZEN's MT 100 To Be Reviewed by Advisory Committee in May 2005 |  |
| December 08, 2004 | POZEN Names Dr. William Stagner Senior Vice President, Program Management and Development Planning |  |
| November 23, 2004 | GlaxoSmithKline Confirms Strong Pipeline Momentum |  |
| November 23, 2004 | GlaxoSmithKline Reviews Novel Therapeutics for CNS Disorders and Confirms Strong Pipeline Momentum |  |
| November 03, 2004 | POZEN To Present at CIBC World Markets Healthcare Conference |  |
| October 27, 2004 | POZEN Reports Third Quarter 2004 Results |  |
| October 19, 2004 | POZEN Names Dr. Marshall Reese Executive Vice President, Product Development |  |
| October 13, 2004 | POZEN Announces October 27 Webcast of Third Quarter Results |  |
| September 20, 2004 | POZEN To Present at UBS 2004 Global Life Sciences Conference |  |
| September 08, 2004 | POZEN to Present at Bear Stearns 17th Annual Healthcare Conference |  |
| August 03, 2004 | POZEN Names William L. Hodges CFO and Senior Vice President, Finance & Administration |  |
| July 29, 2004 | POZEN Reports Second Quarter 2004 Results; POZEN Reports Profitability for the First Time in Company History |  |
| July 22, 2004 | POZEN Announces July 29 Webcast of Second Quarter Results |  |
| June 01, 2004 | POZEN Announces Receipt of Not-Approvable Letter for MT 100 |  |
| May 20, 2004 | Arthur S. Kirsch Appointed to POZEN's Board of Directors |  |
| May 18, 2004 | POZEN and GSK Announce Start of Phase III Program for Trexima, a Novel Migraine Treatment; POZEN Will Receive Phase III Initiation Milestone Payment of $15 Million |  |
| April 29, 2004 | POZEN Reports First Quarter 2004 Results |  |
| April 27, 2004 | POZEN to Present at the Deutsche Bank Health Care Conference |  |
| April 22, 2004 | Pozen Announces April 29 Webcast of First Quarter Results |  |
| March 18, 2004 | POZEN CEO To Present at the Wells Fargo Securities Health Care Conference |  |
| February 19, 2004 | POZEN CEO to Present at the 4th Annual Smith Barney Specialty Pharmaceutical Conference |  |
| February 18, 2004 | POZEN Reports Fourth Quarter and Full-Year 2003 Results; POZEN Books Revenue and Achieves Positive Cash Flow in 2003 |  |
| February 12, 2004 | POZEN Announces February 18 Webcast of Fourth Quarter and Full-Year 2003 Results |  |
| January 28, 2004 | POZEN Announces Favorable Results of Rat Carcinogenicity Study for MT 100 and Submission of Study Report to FDA |  |
| January 27, 2004 | POZEN To Host January 28 Webcast to Discuss Results of Rat Carcinogenicity Study For MT 100 |  |
| January 23, 2004 | POZEN CEO To Present at the U.S. Bancorp Piper Jaffray Health Care Conference |  |
| January 20, 2004 | POZEN Announces Resignation of Chief Financial Officer |  |