Webcast DURECT Corporation at Cowen and Company Healthcare Conference (Replay) 03/08/10 at 3:15 p.m. ET

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Date Title   03/01/10 DURECT to Present at the Cowen and Company Healthcare Conference 02/24/10 DURECT Corporation Announces Fourth Quarter and Year End 2009 Financial Results 02/22/10 DURECT and Nycomed Amend POSIDUR(TM) License Agreement to Separate Funding and Control of U.S. and E.U. Clinical Programs and to Expand Territory 02/17/10 DURECT Corporation Invites You to Join Its Fourth Quarter 2009 Earnings Conference Call 01/19/10 DURECT Initiates U.S. Pivotal Phase III POSIDUR(TM) Clinical Trial