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Analyst Ratings

1-Strong Buy	3
2-Buy	1
3-Hold	0
4-Underperform	0
5-Sell	0

Mean Recommendation: 1.3
Sell		Strong Buy

Analyst Forecasts -
							Last Month Revisions
Fiscal Period	Date	Mean	High	Low	Median	# of Estimates	#Up	#Down	Mean % Change
Annual	12/01/12	-0.08	-0.04	-0.10	-0.10	3	0	0	14.29
Annual	12/01/11	-0.29	-0.25	-0.35	-0.29	4	0	0	-2.50
Annual	12/01/10	-0.34	-0.27	-0.40	-0.35	4	0	1	N/A
Quarterly	03/01/10	-0.09	-0.07	-0.10	-0.10	3	0	0	28.57
Quarterly	06/01/10	-0.09	-0.07	-0.10	-0.09	3	0	0	23.81
Quarterly	09/01/10	-0.08	-0.06	-0.10	-0.09	3	0	0	38.89
Quarterly	12/01/10	-0.09	-0.07	-0.10	-0.09	3	0	0	23.81
Long Term Growth		20.00	20.00	20.00	20.00	1	0	0	0.00

Actuals -
Fiscal Period	Date	Reported EPS	Mean Estimate	Surprise % Change
Annual	12/01/09	-0.37	-0.34	-8.82
Quarterly	03/01/09	-0.11	-0.09	-26.92
Quarterly	06/01/09	-0.09	-0.10	12.20
Quarterly	09/01/09	-0.07	-0.09	22.22
Quarterly	12/01/09	-0.10	-0.07	-42.86
Annual	12/01/08	-0.58	-0.44	-33.33
Annual	12/01/07	-0.35	-0.35	-0.36

Data Provided by Thomson Reuters

DURECT Corporation is followed by various analysts. Please note that any opinions, estimates or forecasts regarding DURECT Corporation's performance made by these analysts are theirs alone and do not represent opinions, forecasts or predictions of DURECT Corporation or its management. DURECT Corporation does not by its reference above or distribution imply its endorsement of or concurrence with such information, conclusions or recommendations.

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Last updated: September 20, 2006