PRESS RELEASES
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| Amylin Pharmaceuticals and Takeda Enter into Worldwide Agreement to Co-Develop and Commercialize Compounds for Obesity |
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The agreement includes products to be developed from Amylin's pipeline, including pramlintide/metreleptin and davalintide, which are compounds currently in phase 2 development for treatment of obesity. The agreement also includes additional compounds from both companies' obesity research programs. Amylin will receive a one-time up-front payment of Under the terms of the agreement, Amylin will be responsible for executing development activities for potential products through phase 2 with the aim of regulatory approval in the U.S. Takeda will lead development activities beyond phase 2 in the U.S., and all development activities outside the U.S. In most instances, Amylin will be responsible for 20% of development costs associated with obtaining approval for products in the U.S. and Takeda will be responsible for 80% of such U.S. development costs. Takeda will be responsible for 100% of development costs associated with obtaining approval for products outside the U.S. Takeda will lead product commercialization, both in the U.S. and outside the U.S., and will be responsible for 100% of commercialization costs. Amylin will have the option to co-commercialize the first two approved products in the U.S. and any follow-on products containing the identical active ingredients. "Takeda is excited to realize this partnership with Amylin focused on the treatment of obesity and related indications. By leveraging Takeda's global development and commercial infrastructure we look forward to maximizing the significant potential of the products under this agreement," said "This collaboration will leverage Amylin's experience and expertise with peptide and protein science and Takeda's worldwide development and commercial expertise," said About Obesity Obesity is rapidly becoming a major health problem in all industrialized nations and many developing countries. It has reached epidemic proportions globally, with more than 1 billion adults overweight, and at least 300 million of them obese. Obesity is a chronic disorder that is linked to increased health risk of several medical conditions including type 2 diabetes, non-alcoholic fatty liver disease, high blood pressure, heart disease, stroke, osteoarthritis, sleep disorders and several types of cancers. According to About About Takeda Located in Forward-Looking Statements This press release contains forward-looking statements about Takeda and Amylin, which involve risks and uncertainties. The actual results for each Company could differ materially from those discussed due to a number of risks and uncertainties, including that the obesity co-development and commercialization agreement mentioned in this press release will not achieve the results we expect; our clinical trials may not start when planned, be completed in a timely manner and/or confirm previous results; our preclinical studies may not be predictive; our product candidates, including those covered by the co-development and commercialization agreement mentioned in this press release, may not receive regulatory approval; and inherent scientific, regulatory and other risks in the drug development and commercialization process. With respect to Amylin, these and additional risks and uncertainties are described more fully in Amylin's most recently filed SOURCE Anne Erickson, Amylin, +1-858-754-4443, cell, +1-858-349-3195, Anne.Erickson@amylin.com; or Seizo Masuda, Takeda (Japan), +81-3-3278-2037, Masuda_Seizo@takeda.co.jp, or Angela Bechan, Takeda (USA), +1-224-554-5467, ABechan@tpna.com |